Your heart is one of the hardest-working organs in your body; it literally never takes a rest. Beat after beat, hour after hour, day after day, for your entire life, your heart contracts and relaxes a little more than once per second, providing the blood flow that every other organ in your body relies on.
That much effort requires a steady supply of energy. And to perform at optimal function—literally without missing a beat—your heart needs to be able to derive that energy from its fuel (primarily fatty acids and glucose) efficiently and with little waste.4-6
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CoQ10 is essential for the heart to maintain sufficient energy management.1,8 But when CoQ10 levels decline, tissues burn fuel inefficiently, eventually producing oxidative damage and ultimately losing their function. When the heart muscle loses its fuel efficiency, heart failure may occur.4,9
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There are many primary causes of heart failure.9,43 The most common include coronary artery disease and high blood pressure but can also include heart attacks, obesity, and diabetes, all of which place excessive demands on the heart muscle, making it work harder and harder just to produce enough blood flow to sustain life at rest. That extra demand for energy uses up CoQ10, resulting in a loss of fuel efficiency precisely when the heart needs every bit of energy it can generate.9
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http://umm.edu/programs/heart/services/conditions/heart-failure/causes-and-risks. Accessed June 28, 2013.
Chronic oxidative stress is one of the main factors reducing the functioning of the endothelium, the thin layer of cells lining arteries that controls blood flow and pressure.21 Endothelial dysfunction is a major precursor to hypertension, coronary heart disease, and strokes. Since CoQ10 is a unique antioxidant, it makes sense that it would have beneficial effects on endothelial function.
Med Sci Monit. 2013;19:339-46.
Your brain receives the largest proportion of total blood flow from your heart; as a result, it has some of the most volatile fluctuations in bioenergetic demands.54 Because of this, CoQ10 is of tremendous importance in maintaining brain health and preventing neuronal damage.
CNS Neurol Disord Drug Targets. 2013 Apr 4.
CoQ10 is well known for its heart and vascular health benefits.2 By helping the cellular powerhouses known as mitochondria burn fuel more effectively, CoQ10 is able to protect not only the heart but every cell in your body.3
That’s why scientists are growing increasingly fascinated with the role of CoQ10 in tissues beyond the cardiovascular system.2 There is evidence for CoQ10’s protective effects in the brain and nervous system, in asthma and chronic lung disease, in diabetes and the metabolic syndrome, on ocular health, and even on the aging immune system.
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Mitochondrial dysfunction from chronic oxidation and the resulting chronic inflammation are a root cause of neurodegenerative conditions like Alzheimer’s, Parkinson’s, Huntington’s, and ALS (Lou Gehrig’s disease).6,14-18
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Eventually, brain cells overwhelmed by amyloid β-peptide lose their function and die, producing the loss of memory, cognition, and physical function we associate with the disease.
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- Your mitochondria need to burn fuel cleanly and efficiently to assure their own integrity and your own longevity.
- CoQ10 is an essential coenzyme that, when added to the diet, acts as a fuel additive to optimize mitochondrial performance, extracting the most energy with the least damage.